General
Preferred name
PYRITINOL
Synonyms
Pyridoxine disulfide ()
Vitamin B6 disulfide ()
Bonifen ()
Encefabol ()
Pyrithioxin ()
Pyritinol dihydrochloride ()
Pyridoxine disulfide dihydrochloride ()
Vitamin B6 disulfide dihydrochloride ()
Pyrithioxin (dihydrochloride) ()
Pyrithioxin Dihydrochloride ()
Bonifen, Encefabol, Pyritinol, Vitamin B6 disulfide ()
Bonifen Dihydrochloride, Encefabol Dihydrochloride, Pyritinol Dihydrochloride, Vitamin B6 disulfide Dihydrochloride ()
Pyrithioxine ()
Piritinol ()
Pyrithioxine hydrochloride ()
NSC-759229 ()
P&D ID
PD000290
CAS
10049-83-9
1098-97-1
Tags
available
drug
Drug Status
approved
investigational
Max Phase
3.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Pyrithioxin, a pyridine thiol derivatives, could be used in the treatment of traumatic brain injury sequelae and some sorts of cerebral infarct patients with Hemiplegia.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
Pyrithioxin dihydrochloride, a pyridine thiol derivative, is a nootropic which could be used in the treatment of sequelae of brain trauma, encephalitis and meningitis as well as the prevention of some cerebrovascular diseases.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
13
BOC Sciences Bioactive Compounds
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMatrix
MedChem Express Bioactive Compound Library
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
41
Molecular Weight
368.09
Hydrogen Bond Acceptors
8
Hydrogen Bond Donors
4
Rotatable Bonds
7
Ring Count
2
Aromatic Ring Count
2
cLogP
2.57
TPSA
106.7
Fraction CSP3
0.38
Chiral centers
0.0
Largest ring
6.0
QED
0.44
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Endogenous Metabolite
Pathway
Metabolic Enzyme/Protease
Indication
rheumatoid arthritis, senile dementia
Disease Area
rheumatology, neurology/psychiatry
Solubility
10mM in DMSO
H2O: ≥ 41 mg/mL
Source data
