General
Preferred name
NADOLOL
Synonyms
Corgard ()
Solgol ()
Anabet ()
SQ11725 ()
Corgard, Solgol, Anabet, SQ11725 ()
P&D ID
PD001017
CAS
42200-33-9
220045-89-6
Tags
natural product
drug
available
Drug indication
High blood pressure
Drug Status
approved
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
The approved drug nadolol consists of equimolar amounts of four stereoisomers, therefore structures shown on other sites may vary in the representation of the stereochemistry. The structure shown here is representative of one of these isomers.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
17
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
DrugBank
DrugBank Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Guide to Pharmacology
NCATS Inxight Approved Drugs
NIH Clinical Collections (NCC)
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
31
Molecular Weight
309.19
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
4
Rotatable Bonds
5
Ring Count
2
Aromatic Ring Count
1
cLogP
0.63
TPSA
81.95
Fraction CSP3
0.65
Chiral centers
3.0
Largest ring
6.0
QED
0.64
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Target
??-adrenergic receptor
Adrenergic Receptor
Therapeutic Class
Antihypertensive Agents
Source data
