General
Preferred name
DIOSMIN
Synonyms
Barosmin ()
Venosmine ()
Diosmil ()
Diosmin ()
Diosven ()
Insuven ()
Litosmil ()
Flebavena ()
NSC-758417 ()
Buchu resin ()
Dioven ()
Daflon ()
Hemerven ()
Flebosten ()
Varinon ()
Tovene ()
Ven-detrex ()
Diovenor ()
Flebaven ()
HESPERIDIN ()
Diosmetin 7-rutinoside ()
Flebosmil ()
P&D ID
PD001043
CAS
520-27-4
111804-73-0
Tags
natural product
drug
available
Drug Status
investigational
approved
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Cell lines
1
Organisms
0
Compound Sets
17
AdooQ Bioactive Compound Library
A10317
Cayman Chemical Bioactives
19848
ChEMBL Approved Drugs
CHEMBL231884
ChEMBL Drugs
CHEMBL231884
Drug Repurposing Hub
DrugBank
DB08995
DrugBank Approved Drugs
DB08995
DrugCentral
3157
DrugCentral Approved Drugs
3157
Mcule NIBR MoA Box Subset
MCULE-3603671410
Novartis Chemogenetic Library (NIBR MoA Box)
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
Diosmin
TargetMol Bioactive Compound Library
T0878
The Spectrum Collection
External IDs
37
Properties
(calculated by RDKit )
Molecular Weight
608.17
Hydrogen Bond Acceptors
15
Hydrogen Bond Donors
8
Rotatable Bonds
7
Ring Count
5
Aromatic Ring Count
3
cLogP
-1.09
TPSA
238.2
Fraction CSP3
0.46
Chiral centers
10.0
Largest ring
6.0
QED
0.16
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Neuroscience
Target
Norepinephrine (NE)
AHR
MOA
Norepinephrine
Aryl Hydrocarbon Receptor (AhR) Agonists
aryl hydrocarbon receptor agonist, capillary stabilizing agent
Member status
member
Indication
chronic venous insufficiency (CVI), edema, deep vein thrombosis (DVT), statis dermatitis, heavy leg syndrome
Disease Area
cardiology, hematology, dermatology
Source data