General
Preferred name
GALANGIN
Synonyms
3,5,7-trihydroxyflavone ()
Norizalpinin ()
NSC-407229 ()
P&D ID
PD001197
CAS
548-83-4
Tags
natural product
drug candidate
nuisance
available
Drug indication
Discovery agent
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION A flavonoid found in high concentrations in Alpinia officinarum.
DESCRIPTION A flavonol found in high concentrations in Alpinia officinarum and other members of the ginger family, that is used in traditional Chinese medicine. (GtoPdb)
DESCRIPTION TRPC5 inhibitor (Tocris Bioactive Compound Library)
Cell lines
6
Organisms
5
Compound Sets
14
AdooQ Bioactive Compound Library
A14607
Cayman Chemical Bioactives
15948
Concise Guide to Pharmacology 2019/20
410
Concise Guide to Pharmacology 2021/22
410
Concise Guide to Pharmacology 2023/24
410
DrugMAP
DM5TQ2O
EU-OPENSCREEN Bioactive Compound Library
EOS100562
Guide to Pharmacology
410
MedChem Express Bioactive Compound Library
HY-N0382
Nuisance compounds in cellular assays
Selleckchem Bioactive Compound Library
galangin
TargetMol Bioactive Compound Library
T3668
The Spectrum Collection
Tocris Bioactive Compound Library
6494
External IDs
32
Properties
(calculated by RDKit )
Molecular Weight
270.05
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
3
Rotatable Bonds
1
Ring Count
3
Aromatic Ring Count
3
cLogP
2.58
TPSA
90.9
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.63
Structural alerts
1
Nonspecific/NOS
Flavonoid
Nuisance compounds in cellular assays
Custom attributes
(extracted from source data)
Pathway
MAPK
NF-??b
Autophagy
Metabolic Enzyme/Protease
Target
ERK
NF-??B
Cytochrome P450
P450 (e.g. CYP17)
Primary Target
TRPC
MOA
Inhibitor
Source data