General
Preferred name
ALLANTOIN
Synonyms
Fluocortolone pivalate ()
5-Ureidohydantoin ()
Glyoxyldiureide ()
Glyoxyldiureide, 5-Ureidohydantoin ()
Septalan ()
Sd 101 ()
Idelalisib metabolite m1a ()
Cordianine ()
Alwextin ()
Dl-allantoin ()
NSC-7606 ()
Psoralon ()
Alcloxa ()
P&D ID
PD001580
CAS
97-59-6
37305-69-4
1317-25-5
Tags
natural product
drug
available
Approved by
FDA
Drug Status
investigational
approved
Max Phase
2.0
Drug indication
Vulnerary (topical)
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
TOXICITY
No studies on repeated dose toxicity and reproductive toxicity have been submitted. Moreover, studies show that the tumor incidence in allantoin treated animals did not differ largely from that found in untreated controls. As a result, further or additional toxicity, mutagenicity, or carcinogenicity tests are not required in view of the endogenous nature of allantoin and the general lack of overall toxicity [FDA Label].; ; Finally, as allantoin is a normal component of the diet in humans and is a substance of endogenous origin present in the body of humans, it is generally recognized as being a safe substance for humans [FDA Label].
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
1
Organisms
0
Compound Sets
16
AdooQ Bioactive Compound Library
ChEMBL Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMatrix
Enamine BioReference Compounds
MedChem Express Bioactive Compound Library
NCATS Inxight Approved Drugs
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
42
Molecular Weight
158.04
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
4
Rotatable Bonds
1
Ring Count
1
Aromatic Ring Count
0
cLogP
-2.18
TPSA
113.32
Fraction CSP3
0.25
Chiral centers
1.0
Largest ring
5.0
QED
0.33
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Metabolism
Metabolic Enzyme/Protease
Neuronal Signaling
Target
Endogenous Metabolite
Imidazoline Receptor
Source data
