General
Preferred name
MYCOPHENOLIC ACID
Synonyms
Mycophenolic acid D3 ()
Mycophenolate D3 ()
RS-61443 ()
Mycophenolate ()
RS-61443 D3 ()
Mycophenolate, RS-61443 ()
Mycophenolic Acid ()
4-Methylumbelliferyl-?-L-Iduronide 2-sulfate (sodium salt) ()
Mycophenolate mofetil impurity, mycophenolic acid- ()
68618 ()
Myfortic ()
RS-61443 [as mofetil] ()
NSC-129185 ()
Mycophenolic sod ()
ERL 080 ()
Mycophenolic acid sodium salt ()
Sodium mycophenalate ()
Ceptava ()
NSC-116072 ()
ERL-080 ()
MYCOPHENOLATE SODIUM ()
P&D ID
PD001641
CAS
24280-93-1
483-60-3
1162256-90-7
37415-62-6
Tags
available
natural product
drug
Approved by
FDA
First approval
2004
Drug indication
Antineoplastic
Organ transplant rejection
Middle East Respiratory Syndrome (MERS)
Drug Status
investigational
approved
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION An antibacterial substance derived from Penicillium stoloniferum, and related species. Inhibits inosine-5'-monophosphate dehydrogenase (IMPDH). (GtoPdb)
DESCRIPTION Cyclooxygenase (COX-1) inhibitor (Tocris Bioactive Compound Library)
DESCRIPTION Inosine monophosphatase dehydrogenase inhibitor (Tocriscreen Plus)
DESCRIPTION Inosine monophosphatase dehydrogenase inhibitor (Tocriscreen Total)
Cell lines
22
Organisms
24
Compound Sets
34
AdooQ Bioactive Compound Library
A10614
Cayman Chemical Bioactives
21716
9001600
CeMM library of unique drugs (CLOUD)
ChEMBL Approved Drugs
CHEMBL866
CHEMBL2106643
ChEMBL Drugs
CHEMBL866
CHEMBL2106643
Concise Guide to Pharmacology 2017/18
6832
Concise Guide to Pharmacology 2019/20
6832
Concise Guide to Pharmacology 2021/22
6832
Concise Guide to Pharmacology 2023/24
6832
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
DrugBank
DB01024
DrugBank Approved Drugs
DB01024
DrugCentral
1860
DrugCentral Approved Drugs
1860
DrugMAP
DMU65NK
DMYTN18
DrugMAP Approved Drugs
DMYTN18
Enamine BioReference Compounds
EU-OPENSCREEN Bioactive Compound Library
EOS100675
Guide to Pharmacology
6832
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL866
MedChem Express Bioactive Compound Library
HY-B0421
NCATS Inxight Approved Drugs
HU9DX48N0T
Novartis Chemogenetic Library (NIBR MoA Box)
NPC Screening Collection
Other bioactive compounds
ReFrame library
Selleckchem Bioactive Compound Library
Mycophenolic-acid(Mycophenolate)
TargetMol Bioactive Compound Library
T1335
The Spectrum Collection
Tocris Bioactive Compound Library
1505
Tocriscreen Plus
1505
Tocriscreen Total
ZINC Tool Compounds
ZINC000000001758
External IDs
66
Properties
(calculated by RDKit )
Molecular Weight
320.13
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
2
Rotatable Bonds
6
Ring Count
2
Aromatic Ring Count
1
cLogP
2.73
TPSA
93.06
Fraction CSP3
0.41
Chiral centers
0.0
Largest ring
6.0
QED
0.62
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target Type
Enzymes
MOA
bacterial inosine-5-monophosphate dehydrogenase inhibitor
Inhibitor
Inosine 5'-Monophosphate Dehydrogenase (IMPDH) Inhibitors
Immunosuppressant
IMPDH inhibitor
Antiviral
dehydrogenase inhibitor, inositol monophosphatase inhibitor
Target
Inosine-5'-monophosphate dehydrogenase (IMPDH)
DH
UGT
IMPDH1, IMPDH2
antibiotic
Bacterial
Dengue virus
Endogenous Metabolite
Flavivirus
Fungal
Antineoplastic and Immunosuppressive Antibiotics,Dehydrogenase,Selection Antibiotics for Transfected Cell
Pathway
Metabolism
Anti-infection
Apoptosis
Metabolic Enzyme/Protease
Primary Target
Other Dehydrogenases
Member status
virtual
Indication
organ rejection
Therapeutic Class
Antiviral Agents
Source data