General
Preferred name
SULFAMETHAZINE
Synonyms
SULFAMERAZINE ()
Sulfadimerazine ()
sulfadimidine ()
Sulfamethazine sodium salt ()
Sulfamethazine ()
Sulfadimidine (sodium) ()
Sulfadimerazine (sodium) ()
Sulfamethazine (sodium) ()
Sulfadimidine,Sulfadimerazine ()
Sulfadimethyldiazine Sodium Salt ()
Sulfamethazine-d4 ()
Sulfamidine ()
Sulfadimidinum ()
NSC-683529 ()
Sulfadimethylpyrimidine ()
NSC-67457 ()
Sulfamezathine ('S-Mez') ()
BN-2409 ()
Smz-Med 454 ()
Sulfamezathine ()
P&D ID
PD001748
CAS
57-68-1
1981-58-4
1020719-82-7
Tags
available
natural product
drug
Approved by
FDA
First approval
1949
Drug indication
Antibacterial
Bacterial infection
Drug Status
investigational
withdrawn
approved
vet_approved
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Sulfadimidine (sulfamethazine) is a sulfonamide antibacterial compound. This class of compounds are competitive inhibitors of bacterial dihydropteroate synthase (DHPS), an enzyme in the pathway which generates the folic acid that is essential for bacterial growth. (GtoPdb)
Compound Sets
22
Cayman Chemical Bioactives
20976
36575
ChEMBL Approved Drugs
CHEMBL446
ChEMBL Drugs
CHEMBL446
Drug Repurposing Hub
DrugBank
DB01582
DrugBank Approved Drugs
DB01582
DrugCentral
2502
DrugCentral Approved Drugs
2502
DrugMAP
DMRGZ16
DrugMAP Approved Drugs
DMRGZ16
DrugMatrix
Enamine BioReference Compounds
Guide to Pharmacology
12642
MedChem Express Bioactive Compound Library
HY-B0035
HY-B0035A
NPC Screening Collection
Other bioactive compounds
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
sulfamethazine
sulfamethazine-sodium-salt
TargetMol Bioactive Compound Library
T0741
The Spectrum Collection
Withdrawn 2.0
56
External IDs
62
Properties
(calculated by RDKit )
Molecular Weight
278.08
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
2
Aromatic Ring Count
2
cLogP
1.48
TPSA
97.97
Fraction CSP3
0.17
Chiral centers
0.0
Largest ring
6.0
QED
0.83
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Microbiology&virology
Anti-infection
Target
antibiotic
Bacterial
MOA
Antibiotic
PABA antagonist
Indication
enteritis
ATC
J01EB03
Therapeutic Class
Antiinfective Agents
Source data