General
Preferred name
PRAZIQUANTEL
Synonyms
Praziquantel D11 ()
Droncit ()
Biltricide ()
Pyquiton ()
Praziquantel (Biltricide) ()
2-(CYCLOHEXYLCARBONYL)-1,2,3,6,7,11B-HEXAHYDRO-4H-PYRAZINO(2,1-A)ISOQUINOLIN-4-ONE ()
Praziquantel-d11 ()
Cisticid ()
Praziquantelum ()
NSC-757285 ()
EMBAY 8440 ()
Cestocur ()
EMBAY-8440 ()
Cysticide ()
Cesol ()
P&D ID
PD001793
CAS
55268-74-1
57452-31-0
135526-78-2
1246343-36-1
Tags
natural product
drug
available
Approved by
FDA
First approval
1982
Drug indication
Flatworm infection
Anthelmintic (veterinary)
Drug Status
investigational
vet_approved
approved
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Ca2+ Ionophore; anthelmintic (LOPAC library)
Cell lines
0
Organisms
4
Compound Sets
25
AdooQ Bioactive Compound Library
A10750
Cayman Chemical Bioactives
20508
30237
CeMM library of unique drugs (CLOUD)
ChEMBL Approved Drugs
CHEMBL976
ChEMBL Drugs
CHEMBL976
CZ-OPENSCREEN Bioactive Library
DrugBank
DB01058
DrugBank Approved Drugs
DB01058
DrugCentral
2241
DrugCentral Approved Drugs
2241
DrugMAP
DMOU1PK
DrugMAP Approved Drugs
DMOU1PK
DrugMatrix
Enamine BioReference Compounds
LOPAC library
MedChem Express Bioactive Compound Library
HY-B0244
NCATS Inxight Approved Drugs
6490C9U457
NIH Clinical Collections (NCC)
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
Praziquantel(Biltricide)
TargetMol Bioactive Compound Library
T1435
The Pathogen Box
The Spectrum Collection
External IDs
50
Properties
(calculated by RDKit )
Molecular Weight
312.18
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
0
Rotatable Bonds
1
Ring Count
4
Aromatic Ring Count
1
cLogP
2.53
TPSA
40.62
Fraction CSP3
0.58
Chiral centers
1.0
Largest ring
6.0
QED
0.8
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
MOA
Unknown molecular target
Selectivity
Ca2+ Ionophore
Target
Parasite
Voltage-activated calcium channel beta 1 subunit
Voltage-activated calcium channel beta 2 subunit
Calcium Channel
antibiotic
COVID-19,Parasite
Disease
REFERENCE COMPOUNDS
Pathway
Anti-infection
Membrane Transporter/Ion Channel
Therapeutic Class
Anthelmintics
Source data