General
Preferred name
PINDOLOL
Synonyms
(S)-(-)-Pindolol ()
PINDOLOL,(+) ()
PINDOLOL,(+/-) ()
PINDOLOL,(-) ()
LB-46 ()
Carvisken ()
Dl-pindolol ()
Decreten ()
Pynastin ()
Betadren ()
Blocklin-l ()
Calvisken ()
Pectobloc ()
Durapindol ()
Pinbetol ()
Glauco-visken ()
Prinodolol ()
NSC-757276 ()
Betapindol ()
Visken ()
Dl-lb-46 ()
Apo-pindol ()
(rs)-pindolol ()
(RS)-PINDOLOL ()
APO-PINDOL ()
BETADREN ()
BLOCKLIN-L ()
CALVISKEN ()
CARVISKEN ()
DECRETEN ()
DL-LB-46 ()
DL-PINDOLOL ()
DURAPINDOL ()
GLAUCO-VISKEN ()
PECTOBLOC ()
PINBETOL ()
PRINODOLOL ()
PYNASTIN ()
P&D ID
PD001798
CAS
13523-86-9
Tags
biased GPCR ligand
natural product
drug
available
Approved by
FDA
First approval
1982
Drug indication
Vasodilator
Hypertension
Drug Status
investigational
approved
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Pindolol is a nonselective beta blocker. (GtoPdb)
DESCRIPTION Nonselective beta adrenoceptor antagonist; vasodilator (LOPAC library)
DESCRIPTION β3 partial agonist (Tocriscreen Total)
Cell lines
0
Organisms
1
Compound Sets
32
BiasDB
Pindolol
Cayman Chemical Bioactives
21445
ChEMBL Approved Drugs
CHEMBL500
ChEMBL Drugs
CHEMBL500
Concise Guide to Pharmacology 2017/18
91
Concise Guide to Pharmacology 2019/20
91
Concise Guide to Pharmacology 2021/22
91
CZ-OPENSCREEN Bioactive Library
DrugBank
DB00960
DrugBank Approved Drugs
DB00960
DrugCentral
2176
DrugCentral Approved Drugs
2176
DrugMAP
DMD2NV7
DrugMAP Approved Drugs
DMD2NV7
DrugMatrix
EU-OPENSCREEN Bioactive Compound Library
EOS101646
EUbOPEN Chemogenomics Library
Guide to Pharmacology
91
Ki Database
PINDOLOL,(-)
PINDOLOL,(+/-)
PINDOLOL,(+)
LOPAC library
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL500
Mcule NIBR MoA Box Subset
MCULE-7764948919
MedChem Express Bioactive Compound Library
HY-B0982
NCATS Inxight Approved Drugs
BJ4HF6IU1D
NIH Clinical Collections (NCC)
Novartis Chemogenetic Library (NIBR MoA Box)
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
pindolol
The Spectrum Collection
Tocriscreen Total
External IDs
36
Properties
(calculated by RDKit )
Molecular Weight
248.15
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
3
Rotatable Bonds
6
Ring Count
2
Aromatic Ring Count
2
cLogP
1.91
TPSA
57.28
Fraction CSP3
0.43
Chiral centers
1.0
Largest ring
6.0
QED
0.73
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
beta
Member status
member
MOA
beta-Adrenoceptor Antagonists
Therapeutic Class
Antihypertensive Agents
Pathway
GPCR/G protein
Neuronal Signaling
Target
5-HT Receptor
Adrenergic Receptor
Recommended Cell Concentration
None
Source data