General
Preferred name
NICERGOLINE
Synonyms
Nimergoline ()
Nicergolinum ()
nicergoline SR, Ethypharm ()
Nilogrin ()
FI-6714 ()
Dilasenil ()
Ergobel ()
Duracebrol ()
Sermion ()
NSC-150531 ()
Circo-maren ()
Vasospan ()
Memoq ()
Nicergolent ()
Ergotop ()
Nicergolina ()
Cergodum ()
P&D ID
PD001880
CAS
27848-84-6
Tags
available
drug
Drug indication
Vasodilator
Brain ischaemia
Senile dementia
Drug Status
approved
investigational
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
17
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
35
Properties
(calculated by RDKit )
Molecular Weight
483.12
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
0
Rotatable Bonds
4
Ring Count
5
Aromatic Ring Count
3
cLogP
3.91
TPSA
56.59
Fraction CSP3
0.42
Chiral centers
3.0
Largest ring
6.0
QED
0.53
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Neuroscience
GPCR/G protein
Neuronal Signaling
Target
Adrenergic Receptor
ADRA1A
Indication
Raynaud's disease, migraine headache, atherosclerosis, thrombosis
Disease Area
rheumatology, neurology/psychiatry, cardiology, hematology
MOA
Adrenergic Receptor antagonist
Therapeutic Class
Vasodilator Agents
Source data
