General
Preferred name
HYPOXANTHINE
Synonyms
Purin-6(1h)-one ()
Sarcine ()
Purin-6-ol ()
Sarkin ()
6-Hydroxypurine ()
Hypoxanthine-d4 ()
P&D ID
PD001959
CAS
68-94-0
184856-40-4
2483831-32-7
Tags
available
drug candidate
Drug indication
Discovery agent
Drug Status
experimental
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Hypoxanthine is a naturally occurring purine derivative. (BOC Sciences Bioactive Compounds)
Cell lines
0
Organisms
1
Compound Sets
16
BOC Sciences Bioactive Compounds
hypoxanthine-cas-68-94-0-185187
Cayman Chemical Bioactives
22254
36330
Concise Guide to Pharmacology 2017/18
4555
Concise Guide to Pharmacology 2019/20
4555
Concise Guide to Pharmacology 2021/22
4555
Concise Guide to Pharmacology 2023/24
4555
Drug Repurposing Hub
DrugBank
DB04076
DrugMAP
DMLSABI
Guide to Pharmacology
4555
Ki Database
Hypoxanthine
MedChem Express Bioactive Compound Library
HY-N0091
NPC Screening Collection
Selleckchem Bioactive Compound Library
hypoxanthine
TargetMol Bioactive Compound Library
T1362
The Spectrum Collection
External IDs
57
Properties
(calculated by RDKit )
Molecular Weight
136.04
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
0
Ring Count
2
Aromatic Ring Count
2
cLogP
-0.35
TPSA
74.43
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.52
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Purine nucleoside phosphorylase
PNP
Endogenous Metabolite
MOA
PARP inhibitor
Pathway
Metabolic Enzyme/Protease
Solubility
Soluble in Aqueous Base (Slightly, Heated), DMSO (Slightly, Heated)
Source data