General
Preferred name
dantron
Synonyms
DANTHRON ()
1,8-Dihydroxyanthraquinone ()
NSC7210 ()
Chrysazin ()
Antrapurol ()
chrysazin, Antrapurol ()
NSC-646568 ()
Pilules vinchy n.f. ()
NSC-38626 ()
Dantron ()
P&D ID
PD002124
CAS
117-10-2
Tags
available
natural product
drug
Approved by
MHRA
First approval
1994
Drug Status
investigational
withdrawn
approved
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Cell lines
1
Organisms
0
Compound Sets
18
Bioprocess diversity set
ChEMBL Approved Drugs
CHEMBL53418
ChEMBL Drugs
CHEMBL53418
Drug Repurposing Hub
DrugBank
DB04816
DrugBank Approved Drugs
DB04816
DrugCentral
3125
DrugCentral Approved Drugs
3125
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL53418
MedChem Express Bioactive Compound Library
HY-B0923
NIH Mechanistic Set
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
danthron
TargetMol Bioactive Compound Library
T0800
The Spectrum Collection
Withdrawn 2.0
w108
External IDs
38
Properties
(calculated by RDKit )
Molecular Weight
240.04
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
2
Rotatable Bonds
0
Ring Count
3
Aromatic Ring Count
2
cLogP
1.87
TPSA
74.6
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.63
Structural alerts
1
quinone_A(370)
[!#6&!#1]=[#6]-1-[#6]=,:[#6]-[#6](=[!#6&!#1])-[#6]=,:[#6]-1
PAINS Family A
Related compounds
Custom attributes
(extracted from source data)
Biological process
Cell polarity & morphogenesis
Pathway
PI3K/Akt/mTOR signaling
Anti-infection
Autophagy
Epigenetics
PI3K/Akt/mTOR
Target
AMPK
Bacterial
Virus Protease
MOA
laxative
ATC
A06AB53
Toxicity type
carcinogenicity
Source data