General
Preferred name
SQ 22536
Synonyms
SQ 22,536 ()
9-(tetrahydrofuran-2-yl)-9h-purin-6-amine ()
SQ22536 ()
9-(tetrahydro-2-furyl)-adenine ()
P&D ID
PD002596
CAS
17318-31-9
Tags
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Adenylyl cyclase inhibitor
(Tocriscreen Plus)
DESCRIPTION
Adenylyl cyclase inhibitor
(LOPAC library)
DESCRIPTION
DNA topoisomerase II inhibitor
(Tocris Bioactive Compound Library)
DESCRIPTION
Adenylyl cyclase inhibitor
(Tocriscreen Total)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
11
CZ-OPENSCREEN Bioactive Library
DrugMatrix
LOPAC library
Mcule NIBR MoA Box Subset
MedChem Express Bioactive Compound Library
Novartis Chemogenetic Library (NIBR MoA Box)
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
Tocris Bioactive Compound Library
Tocriscreen Plus
Tocriscreen Total
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
22
Molecular Weight
205.1
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
1
Rotatable Bonds
1
Ring Count
3
Aromatic Ring Count
2
cLogP
0.72
TPSA
78.85
Fraction CSP3
0.44
Chiral centers
1.0
Largest ring
6.0
QED
0.74
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target Type
Enzymes
Selectivity
Adenylyl cyclase
Pathway
Neuroscience
GPCR/G protein
Target
Adenylate cyclase
cAMP
Primary Target
Adenylyl Cyclases
MOA
Inhibitor
Adenylate Cyclase Inhibitors
Member status
member
Source data
