General
Preferred name
OXOLINIC ACID
Synonyms
Urinox ()
NSC 110364 ()
Nidantin ()
Dioxacin ()
Emyrenil ()
NSC-110364 ()
Oxolinate ()
Aqualinic ()
W-4565 ()
Acide oxolinique ()
Acido oxolinico ()
W 4565 ()
Oxolinic ?Acid ()
P&D ID
PD002639
CAS
14698-29-4
Tags
available
drug
Drug Status
experimental
approved
investigational
Max Phase
2.0
Drug indication
Antibacterial
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Oxolinic acid is a quinolone antibacterial compound, with activity against Gram-negative bacteria .
(GtoPdb)
DESCRIPTION
Quinolone antibacterial; DNA gyrase inhibitor
(LOPAC library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
15
Cayman Chemical Bioactives
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMatrix
Guide to Pharmacology
LOPAC library
MedChem Express Bioactive Compound Library
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
35
Molecular Weight
261.06
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
1
Rotatable Bonds
2
Ring Count
3
Aromatic Ring Count
2
cLogP
1.45
TPSA
77.76
Fraction CSP3
0.23
Chiral centers
0.0
Largest ring
6.0
QED
0.88
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
DNA Gyrase
Pathway
GPCR/G protein
DNA Damage/DNA Repair
Microbiology&virology
Neuroscience
Anti-infection
Cell Cycle/DNA Damage
Target
bacterial DNA gyrase
DNA synthesis
dopamine uptake
antibiotic
Bacterial
DNA/RNA Synthesis
MOA
Antibacterial inhibitor
DNA/RNA Synthesis inhibitor
dopamine receptor inhibitor
bacterial DNA gyrase inhibitor
Source data
