General
Preferred name
MEDROXYPROGESTERONE ACETATE
Synonyms
MPA ()
Medroxyprogesterone (acetate) ()
Medroxyprogesterone 17-acetate ()
Farlutin ()
NSC-26386 ()
Metigestrona ()
Provera ()
medroxyprogesterone ()
Medroxyprogesterone (acetate)Medroxyprogesterone 17-acetate ()
Medroxyprogesterone acetate (NSC-26386) ()
MPA, NSC-26386, Medroxyprogesterone 17-acetate, Farlutin ()
Farlutal 200 ()
Farlutal ()
Depo-Provera ()
Adgyn Medro ()
Depo-Provera Oncology ()
Climanor ()
Prempro ()
NSC-21171 ()
Depo-Subq Provera 104 ()
Farlutal 250 ()
Farlutal 100 ()
Depo-Progevera ()
Medroxiprogesterone Acetate ()
Curretab ()
Lunelle ()
TV-46046 ()
Medroxyprogesterone ()
NSC-27408 ()
Farlutal 500 ()
Amen ()
Depot-medroxyprogesterone acetate ()
Sayana Press ()
Medroxyprogesteroni acetas ()
Farlutal inyectable ()
G03AC06 ()
Cycrin ()
Medroxiprogesterona ()
P&D ID
PD003108
CAS
71-58-9
135843-32-2
Tags
available
drug
Approved by
FDA
First approval
1959
Drug Status
approved
investigational
Max Phase
4.0
Drug indication
Progestin
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Cell lines
5
Organisms
0
Compound Sets
17
Cayman Chemical Bioactives
23664
ChEMBL Approved Drugs
CHEMBL717
ChEMBL Drugs
CHEMBL717
Drug Repurposing Hub
DrugBank
DB00603
DrugBank Approved Drugs
DB00603
DrugCentral
1659
DrugCentral Approved Drugs
1659
EU-OPENSCREEN Bioactive Compound Library
EOS100354
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL717
MedChem Express Bioactive Compound Library
HY-B0469
NIH Clinical Collections (NCC)
NPC Screening Collection
NURSA ligand set
nursa/index.jsf?doi=10.1621%2FBZ6C3NDQZY
ReFrame library
Selleckchem Bioactive Compound Library
Medroxyprogesterone-acetate
TargetMol Bioactive Compound Library
T1261
External IDs
45
Properties
(calculated by RDKit )
Molecular Weight
386.25
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
0
Rotatable Bonds
2
Ring Count
4
Aromatic Ring Count
0
cLogP
4.66
TPSA
60.44
Fraction CSP3
0.79
Chiral centers
7.0
Largest ring
6.0
QED
0.65
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Endocrinology/Hormones
Immunology/Inflammation
Metabolic Enzyme/Protease
Vitamin D Related/Nuclear Receptor
Target
ER
PR
ESR1, PGR
Androgen Receptor
Endogenous Metabolite
Glucocorticoid Receptor
Progesterone Receptor
Estrogen/progestogen Receptor
Indication
contraceptive
MOA
Progesterone receptor agonist
Source data