General
Preferred name
AMINOLEVULINIC ACID
Synonyms
AMINOLEVULINIC ACID HYDROCHLORIDE ()
Pentanoic acid, 5-amino-4-oxo- ()
DELTA-AMINOLEVULINIC ACID ()
ALA ()
5-ALA ()
Hydrangin ()
5-Aminolevulinic acid HCl ()
ALA hydrochloride ()
5-Aminolevulinic acid hydrochloride ()
Levulan ()
5-Aminolevulinate hydrochloride ()
.delta.-Aminolevulinic acid hydrochloride ()
Pentanoic acid, 5-amino-4-oxo-, hydrochloride ()
Levulinic acid, 5-amino-, hydrochloride ()
5-ALA (hydrochloride) ()
δ-Aminolevulinic acid (hydrochloride) ()
5-Amino-4-oxopentanoic acid (hydrochloride) ()
Aminolevulinic acid hci ()
5-Aminolevulinic acid (hydrochloride) ()
5-ALA hydrochloride ()
Gleolan ()
Alaglio ()
Alabel ()
Gliolan ()
5 ala hcl (trivial name) ()
Aminolevulinic acid hcl ()
NSC-18509 ()
Ameluz ()
NPC-07 ()
5-aminolevulinic acid ()
.delta.-aminolevulinic acid ()
P&D ID
PD003147
CAS
5451-09-2
106-60-5
Tags
available
drug
covalent binder
Approved by
FDA
First approval
1999
Drug indication
Acne vulgaris
Actinic keratosis
Antineoplastic
Drug Status
approved
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Approved as aminolevulinic acid (GtoPdb)
Compound Sets
28
AdooQ Bioactive Compound Library
A10016
Cayman Chemical Bioactives
9001902
ChEMBL Approved Drugs
CHEMBL1200582
CHEMBL601
ChEMBL Drugs
CHEMBL1200582
CHEMBL601
Concise Guide to Pharmacology 2017/18
4784
Concise Guide to Pharmacology 2019/20
4784
Concise Guide to Pharmacology 2021/22
4784
Concise Guide to Pharmacology 2023/24
4784
CovBinderInPDB
CBR001247
CBR004392
CBR005760
Drug Repurposing Hub
DrugBank
DB00855
DrugBank Approved Drugs
DB00855
DrugCentral
166
DrugCentral Approved Drugs
166
DrugMAP
DMWNHPC
DMS4BLQ
DrugMAP Approved Drugs
DMWNHPC
DMS4BLQ
DrugMatrix
Guide to Pharmacology
4784
MedChem Express Bioactive Compound Library
HY-N0305
Natural product-based probes and drugs
NCATS Inxight Approved Drugs
88755TAZ87
NIH Approved Oncology Drugs
541468
NIH Clinical Collections (NCC)
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
5-Aminolevulinic-acid-hydrochloride
TargetMol Bioactive Compound Library
T1662
The Spectrum Collection
External IDs
86
Properties
(calculated by RDKit )
Molecular Weight
131.06
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
4
Ring Count
0
Aromatic Ring Count
0
cLogP
-0.62
TPSA
80.39
Fraction CSP3
0.6
Chiral centers
0.0
Largest ring
0.0
QED
0.53
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Autophagy
Apoptosis
Metabolic Enzyme/Protease
MOA
Mitophagy
oxidizing agent
Indication
glioma, actinic keratosis (AK)
Disease Area
oncology, dermatology
Target
ALAD
Endogenous Metabolite
Biosynthetic Origin
Other (Amino Acid)
Therapeutic Indication
Anticancer
Source data