General
Preferred name
NNGH
Synonyms
N-ISOBUTYL-N-[4-METHOXYPHENYLSULFONYL]GLYCYL HYDROXAMIC ACID ()
P&D ID
PD005008
CAS
161314-17-6
Tags
available
drug candidate
Drug Status
experimental
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
NNGH is a cell-permeable inhibitor of matrix metalloproteinases (MMPs). It has been used to study the role of MMP-3 (stromelysin 1) in biological systems.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
6
Organisms
0
Compound Sets
5
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
DrugBank
MedChem Express Bioactive Compound Library
ZINC Tool Compounds
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
23
Molecular Weight
316.11
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
2
Rotatable Bonds
7
Ring Count
1
Aromatic Ring Count
1
cLogP
0.85
TPSA
95.94
Fraction CSP3
0.46
Chiral centers
0.0
Largest ring
6.0
QED
0.57
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Metabolic Enzyme/Protease
Target
MMP
Source data
