General
Preferred name
CCT-018159
Synonyms
CCT 018159 ()
CCT018159 ()
P&D ID
PD005041
CAS
171009-07-7
Tags
available
drug candidate
Drug indication
Solid tumour/cancer
Drug Status
experimental
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Hsp90 inhibitor
(Tocriscreen Plus)
DESCRIPTION
Immunomodulator; inhibits IL-10 synthesis and potentiates IL-1alpha, IL-2 and TNF-alpha release
(Tocris Bioactive Compound Library)
DESCRIPTION
Hsp90 inhibitor
(Tocriscreen Total)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
365
Organisms
0
Compound Sets
9
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
24
Molecular Weight
352.14
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
3
Rotatable Bonds
3
Ring Count
4
Aromatic Ring Count
3
cLogP
3.8
TPSA
87.6
Fraction CSP3
0.25
Chiral centers
0.0
Largest ring
6.0
QED
0.67
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target Type
Cell Biology
Primary Target
Hsp90
MOA
Inhibitor
HSP inhibitor
Target
HSP90AA1, HSP90AB1
HSP
Pathway
Apoptosis
Cell Cycle/DNA Damage
Metabolic Enzyme/Protease
Therapeutic Class
Anticancer Agents
Source data
