General
Preferred name
MDL72527
Synonyms
MDL 72527 ()
MDL-72527 ()
MDL 72527 (hydrochloride) ()
P&D ID
PD006896
CAS
93565-01-6
Tags
available
drug candidate
Drug Status
experimental
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
MDL 72527 is a polyamine oxidase inhibitor. It can block the production of H2O2 and increase the cells survival. MDL 72527 shows anticancer and neuroprotective activity in vivo.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
7
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
CZ-OPENSCREEN Bioactive Library
DrugBank
MedChem Express Bioactive Compound Library
Novartis Chemogenetic Library (NIBR MoA Box)
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
42
Molecular Weight
192.16
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
9
Ring Count
0
Aromatic Ring Count
0
cLogP
1.63
TPSA
24.06
Fraction CSP3
0.5
Chiral centers
0.0
Largest ring
0.0
QED
0.43
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Member status
member
MOA
Apoptosis Inducers
Polyamine Oxidase Inhibitors
Source data
