General
Preferred name
Lysergic Acid Diethylamide
Synonyms
LYSERGIDE ()
[3H]LSD ()
Lsd-25 ()
Dextrolysergic acid diethylamide ()
LSD ()
D-lsd ()
Lysergic acid diethylamide tartrate ci ()
N,n-diethyllysergamide ()
Lisergida ()
[3H]LSD ()
LSD (D-tartrate) (solution) ()
LSD (CRM) ()
LSD (L-hemitartrate) (solution) ()
LSD-d10 (D-tartrate) (solution) ()
LSD (D-tartrate) ()
LSD (D-tartrate) ()
P&D ID
PD009135
CAS
50-37-3
32426-57-6
17676-08-3
Tags
available
biased GPCR ligand
drug
drug candidate
First approval
1957
Drug indication
Addictive disorder
Discovery agent
Drug Status
approved
withdrawn
illicit
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Lysergic acid diethylamide (LSD), also known colloquially as "acid", is a psychedelic drug known for its psychological effects. In 2017 LSD was crystalised in complex with the human serotonin receptor 5-HT2B .
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
15
BiasDB
ChEMBL Drugs
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
DrugBank
DrugCentral
DrugCentral Approved Drugs
LSP-MoA library (Laboratory of Systems Pharmacology)
NPC Screening Collection
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
39
Molecular Weight
323.2
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
3
Ring Count
4
Aromatic Ring Count
2
cLogP
2.91
TPSA
39.34
Fraction CSP3
0.45
Chiral centers
2.0
Largest ring
6.0
QED
0.94
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
ATC
N
Source data
