General
Preferred name
THIOPROPERAZINE
Synonyms
Thioproperazine mesilate ()
Thioproperazine dimesylate ()
RP 7843 ()
SKF 5883 ()
Thioperazine ()
Tioproperazina ()
NSC-33232 ()
Thioproperazine dimesilate ()
Thioproperazine Methanesulfonate ()
Thioperazine mesylate ()
Thioproperazine Dimethanesulfonate ()
Thioproperazinum ()
THIOPROPERAZINE MESYLATE ()
P&D ID
PD009442
CAS
2347-80-0
316-81-4
Tags
available
drug candidate
drug
Drug Status
experimental
approved
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
11
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMatrix
Ki Database
MedChem Express Bioactive Compound Library
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
40
Properties
(calculated by RDKit )
Molecular Weight
446.18
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
0
Rotatable Bonds
6
Ring Count
4
Aromatic Ring Count
2
cLogP
3.18
TPSA
47.1
Fraction CSP3
0.45
Chiral centers
0.0
Largest ring
6.0
QED
0.68
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
ADRA1A, ADRA1B, DRD1, DRD2, HTR1A, HTR2A
Dopamine Receptor
Indication
schizophrenia
MOA
Dopamine Receptor antagonist
Pathway
GPCR/G protein
Neuronal Signaling
Source data
