General
Preferred name
THIOPROPERAZINE
Synonyms
Thioproperazine mesilate ()
Thioproperazine dimesylate ()
RP 7843 ()
SKF 5883 ()
Thioperazine ()
Thioproperazine dimesilate ()
Thioperazine mesylate ()
Thioproperazinum ()
Thioproperazine Methanesulfonate ()
Thioproperazine Dimethanesulfonate ()
NSC-33232 ()
THIOPROPERAZINE MESYLATE ()
P&D ID
PD009442
CAS
2347-80-0
316-81-4
Tags
natural product
drug
drug candidate
available
Drug Status
investigational
approved
experimental
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
11
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMatrix
Ki Database
MedChem Express Bioactive Compound Library
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
38
Properties
(calculated by RDKit )
Molecular Weight
446.18
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
0
Rotatable Bonds
6
Ring Count
4
Aromatic Ring Count
2
cLogP
3.18
TPSA
47.1
Fraction CSP3
0.45
Chiral centers
0.0
Largest ring
6.0
QED
0.68
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
ADRA1A, ADRA1B, DRD1, DRD2, HTR1A, HTR2A
Dopamine Receptor
Indication
schizophrenia
MOA
Dopamine Receptor antagonist
Pathway
GPCR/G protein
Neuronal Signaling
Source data
