General
Preferred name
ALVERINE
Synonyms
ALVERINE CITRATE ()
NSC 35459 ()
Alverine citrate salt ()
Alverine (citrate) ()
Gielism ()
Calmabel ()
Antispasmin ()
Proverine ()
Spasmaverine ()
Spacolin ()
Profenil citrate ()
Audmonal ()
NSC-35459 ()
Spasmonal Fte ()
Profenine ()
Phenpropamine Citrate ()
Relaxyl ()
Gamatran citrate ()
Spasmonal ()
Prophelan ()
Phenpropamine ()
Alverina ()
P&D ID
PD009447
CAS
5560-59-8
150-59-4
Tags
available
drug
Drug Status
approved
investigational
Max Phase
4.0
Drug indication
Anticholinergic
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Alverine, a phenpropamine derivative, has been found to be a smooth muscle relaxant that could be used to against the spasm of the stomach, intestines and womb.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
17
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMatrix
MedChem Express Bioactive Compound Library
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
50
Molecular Weight
281.21
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
0
Rotatable Bonds
9
Ring Count
2
Aromatic Ring Count
2
cLogP
4.57
TPSA
3.24
Fraction CSP3
0.4
Chiral centers
0.0
Largest ring
6.0
QED
0.65
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Neuroscience
Neuronal Signaling
Target
5-HT
HTR1A
5-HT Receptor
Indication
irritable bowel syndrome, diverticular disease
MOA
muscle relaxant
Source data
