General
Preferred name
PERICIAZINE
Synonyms
10-(3-(4-Hydroxypiperidino)propyl)phenothiazine-2-carbonitrile ()
Propericiazine ()
RP 8909 ()
Pericyazine ()
NSC-758641 ()
SKF-20716 ()
Neulactil ()
SKF 20716 ()
RP-8909 ()
P&D ID
PD009450
CAS
2622-26-6
Tags
natural product
drug
available
Drug indication
Psychiatric disorder
Drug Status
investigational
approved
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Periciazine is a phenothiazine antipsychotic. It has anti-dopaminergic, adrenolytic, anticholinergic, metabolic and endocrine effects. (GtoPdb)
Cell lines
0
Organisms
1
Compound Sets
15
Cayman Chemical Bioactives
33149
ChEMBL Approved Drugs
CHEMBL251940
ChEMBL Drugs
CHEMBL251940
DrugBank
DB01608
DrugBank Approved Drugs
DB01608
DrugCentral
2107
DrugCentral Approved Drugs
2107
DrugMAP
DME9JNL
DrugMAP Approved Drugs
DME9JNL
DrugMatrix
Guide to Pharmacology
9216
Ki Database
PROPERICIAZINE
MedChem Express Bioactive Compound Library
HY-14263
NPC Screening Collection
ReFrame library
External IDs
30
Properties
(calculated by RDKit )
Molecular Weight
365.16
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
1
Rotatable Bonds
4
Ring Count
4
Aromatic Ring Count
2
cLogP
4.01
TPSA
50.5
Fraction CSP3
0.38
Chiral centers
0.0
Largest ring
6.0
QED
0.89
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Therapeutic Class
Antipsychotic Agents
Pathway
GPCR/G protein
Neuronal Signaling
Target
Dopamine Receptor
Source data