General
Preferred name
AZELASTINE
Synonyms
AZELASTINE HYDROCHLORIDE ()
CPD000469183 ()
Azelastine HCl ()
Optivar ()
Astelin ()
Allergodil ()
Azelastine (hydrochloride) ()
Azelastinum [inn_la] ()
ASTEPRO ALLERGY ()
W-2979M ()
OPTILAST ()
E-0659 ()
RHINOLAST ()
RHINOLAST ALLERGY ()
CHILDREN'S ASTEPRO ALLERGY ()
ASTEPRO ()
A-5610 ()
Azelastina ()
NSC-758971 ()
Azelastine-13C-d3 (hydrochloride) ()
P&D ID
PD009611
CAS
79307-93-0
58581-89-8
2930288-75-6
Tags
available
drug
Approved by
FDA
First approval
1996
Drug indication
Anti-Allergic
Anti-Asthmatic
Allergic conjunctivitis
Drug Status
approved
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION There is no information regarding approval for clinical use of this drug on the US FDA website. Other national approval agencies may have granted marketing authorisation. (GtoPdb)
Cell lines
0
Organisms
3
Compound Sets
30
AdooQ Bioactive Compound Library
A10117
Bioprocess diversity set
Cayman Chemical Bioactives
20873
33295
ChEMBL Approved Drugs
CHEMBL1200809
CHEMBL639
ChEMBL Drugs
CHEMBL1200809
CHEMBL639
Concise Guide to Pharmacology 2017/18
7121
Concise Guide to Pharmacology 2019/20
7121
Concise Guide to Pharmacology 2021/22
7121
Concise Guide to Pharmacology 2023/24
7121
CZ-OPENSCREEN Bioactive Library
DrugBank
DB00972
DrugBank Approved Drugs
DB00972
DrugCentral
271
DrugCentral Approved Drugs
271
DrugMAP
DMXTMBJ
DrugMAP Approved Drugs
DMXTMBJ
DrugMatrix
EU-OPENSCREEN Bioactive Compound Library
EOS101316
EUbOPEN Chemogenomics Library
EUB0000486
Guide to Pharmacology
7121
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL639
MedChem Express Bioactive Compound Library
HY-B0462
NCATS Inxight Approved Drugs
ZQI909440X
NIH Clinical Collections (NCC)
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
azelastine
TargetMol Bioactive Compound Library
T0211L
The Spectrum Collection
External IDs
60
Properties
(calculated by RDKit )
Molecular Weight
381.16
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
0
Rotatable Bonds
3
Ring Count
4
Aromatic Ring Count
3
cLogP
4.3
TPSA
38.13
Fraction CSP3
0.36
Chiral centers
1.0
Largest ring
7.0
QED
0.68
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Biological process
Resipration, oxidative phosphorylation, & mitochondrial targeting
Target
Histamine Receptor
H1 receptor
SARS-CoV
Pathway
Immunology/Inflammation
GPCR/G protein
Neuronal Signaling
Neuroscience
Anti-infection
Therapeutic Class
Antiallergic Agents
Recommended Cell Concentration
None
Source data