General
Preferred name
DIETHYLPROPION
Synonyms
Amfepramone ()
Amfepramone hydrochloride ()
Diethylpropion hydrochloride civ ()
Diethylpropion HCl ()
Dobesin ()
Apisate ()
Regenon ()
Moderatan ()
Prefamone ()
Tepanil Ten-Tab ()
Tenuate Dospan ()
Tepanil ()
D03801 ()
Tenuate ()
Anorex ()
DIETHYLPROPION HYDROCHLORIDE ()
Diethylcathinone ()
C06954 ()
D07444 ()
Anfepramona ()
Anfepramone ()
.alpha.-benzoyltriethylamine ()
Anferpramon ()
J4.327C ()
Diethylpropion ()
Diethylcathinone (hydrochloride) ()
P&D ID
PD009631
CAS
134-80-5
90-84-6
Tags
available
prodrug
drug
Approved by
FDA
First approval
1959
Drug indication
Anorexic
Migraine
Obesity
Drug Status
approved
withdrawn
illicit
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Diethylpropion is a stimulant drug (of the phenethylamine, amphetamine, and cathinone classes) used for its appetite suppressing action.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
15
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Guide to Pharmacology
NCATS Inxight Approved Drugs
NPC Screening Collection
Prestwick Chemical Library
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
54
Molecular Weight
205.15
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
0
Rotatable Bonds
5
Ring Count
1
Aromatic Ring Count
1
cLogP
2.6
TPSA
20.31
Fraction CSP3
0.46
Chiral centers
1.0
Largest ring
6.0
QED
0.69
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
ATC
A08AA03
Toxicity type
cardiovascular
Source data
