General
Preferred name
ACEPROMETAZINE
Synonyms
CB 1664 ()
CB-1664 ()
P&D ID
PD009644
CAS
13461-01-3
Tags
natural product
drug
available
Drug indication
Sleep-wake disorder
Drug Status
investigational
approved
experimental
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Aceprometazine is a Histamine H1 receptor antagonist as an approved drug. It can be used in combination with meprobamate for the treatment of sleep disorders such as Insomnia. (BOC Sciences Bioactive Compounds)
Compound Sets
9
BOC Sciences Bioactive Compounds
ChEMBL Drugs
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
ReFrame library
External IDs
19
Properties
(calculated by RDKit )
Molecular Weight
326.15
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
0
Rotatable Bonds
4
Ring Count
3
Aromatic Ring Count
2
cLogP
4.44
TPSA
23.55
Fraction CSP3
0.32
Chiral centers
1.0
Largest ring
6.0
QED
0.77
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Therapeutic Class
Antihistamines
Solubility
Soluble in DMSO
Source data