General
Preferred name
MINAPRINE
Synonyms
MINAPRINE HYDROCHLORIDE ()
Cantor ()
30038CB ()
Minaprine HCl ()
Minaprine dihydrochloride ()
Minaprinum ()
Minaprina ()
Minaprine (dihydrochloride) ()
Brantur ()
NSC-305742 ()
30038-CB ()
AGR-1240 ()
CB-30038 ()
P&D ID
PD009708
CAS
25953-17-7
25905-77-5
118269-66-2
Tags
available
natural product
drug
Drug indication
Depression
Antidepressant
Antidepressant,Psychotropic
Drug Status
withdrawn
approved
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
22
ChEMBL Approved Drugs
ChEMBL Drugs
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
EU-OPENSCREEN Bioactive Compound Library
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
NPC Screening Collection
Other bioactive compounds
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
52
Properties
(calculated by RDKit )
Molecular Weight
298.18
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
1
Rotatable Bonds
5
Ring Count
3
Aromatic Ring Count
2
cLogP
2.2
TPSA
50.28
Fraction CSP3
0.41
Chiral centers
0.0
Largest ring
6.0
QED
0.92
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Metabolism
Neuroscience
GPCR/G protein
Neuronal Signaling
Target
MAO-A
5-HT
Sert (Sodium-dependent)
mAChR
dopamine
ACHE, CHRM1, DRD1, DRD2, HTR2A, HTR2B, HTR2C, MAOA, SLC6A4
Monoamine Oxidase
MAO
MOA
5-HT Receptor antagonist
AChR inhibitor
Dopamine Receptor agonist
MAO inhibitor
serotonin reuptake inhibitor
ATC
N06AX07
Toxicity type
neurological
Therapeutic Class
Antidepressants
Source data
