General
Preferred name
alimemazine
Synonyms
Temaril ()
Alimemazine Tartrate ()
Vallergan Fte ()
Vallergan ()
TRIMEPRAZINE TARTRATE ()
trimeprazine ()
Alimemazine D6 ()
Trimeprazine D6 ()
Alimemazine hemitartrate ()
Trimeprazine hemitartrate ()
Methylpromazine Tartrate ()
Trimeprazine Tartrate, Methylpromazine Tartrate ()
Trimeprazine (tartrate) ()
BAYER-1219 ()
RP-6549 ()
Alimemazine ()
Dl-trimeprazine ()
METHYLPROMAZINE ()
Repeltin ()
NSC-17475 ()
NSC-757358 ()
Theralene ()
Panectyl ()
P&D ID
PD009940
CAS
4330-99-8
84-96-8
1175-88-8
14101-45-2
41375-66-0
Tags
natural product
drug
available
Approved by
FDA
Drug indication
Antipruritic
Allergic rhinitis
Drug Status
vet_approved
approved
Max Phase
4.0
First approval
1982
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Alimemazine is a phenothiazine derivative antihistamine. (GtoPdb)
Cell lines
1
Organisms
0
Compound Sets
21
Cayman Chemical Bioactives
33891
ChEMBL Approved Drugs
CHEMBL829
CHEMBL3989885
ChEMBL Drugs
CHEMBL829
CHEMBL3989885
DrugBank
DB01246
DrugBank Approved Drugs
DB01246
DrugCentral
2749
DrugCentral Approved Drugs
2749
DrugMAP
DMEMV9D
DrugMAP Approved Drugs
DMEMV9D
DrugMatrix
Guide to Pharmacology
7237
Ki Database
Trimeprazine
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL1713082
MedChem Express Bioactive Compound Library
HY-12752A
NPC Screening Collection
Other bioactive compounds
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
alimemazine-tartrate
TargetMol Bioactive Compound Library
T3282
The Spectrum Collection
External IDs
74
Properties
(calculated by RDKit )
Molecular Weight
298.15
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
0
Rotatable Bonds
4
Ring Count
3
Aromatic Ring Count
2
cLogP
4.49
TPSA
6.48
Fraction CSP3
0.33
Chiral centers
1.0
Largest ring
6.0
QED
0.82
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Histamine Receptor
Pathway
Immunology/Inflammation
GPCR/G protein
Neuronal Signaling
Therapeutic Class
Antihistamines
Source data