General
Preferred name
ISOLEUCINE
Synonyms
L-isoleucine ()
Ile ()
L-Isoleucine ()
Isoleucina ()
FEMA NO. 4675 ()
NSC-46708 ()
L-Isoleucine-13C6 ()
P&D ID
PD010191
CAS
73-32-5
34464-35-2
410078-51-2
1160211-67-5
443-79-8
201740-82-1
Tags
available
drug
Approved by
FDA
Drug indication
Discovery agent
Amino Acid
Drug Status
approved
investigational
nutraceutical
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
16
Cayman Chemical Bioactives
ChEMBL Drugs
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMAP
Guide to Pharmacology
MedChem Express Bioactive Compound Library
Novartis Chemogenetic Library (NIBR MoA Box)
NPC Screening Collection
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
61
Properties
(calculated by RDKit )
Molecular Weight
131.09
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
0
Aromatic Ring Count
0
cLogP
0.44
TPSA
63.32
Fraction CSP3
0.83
Chiral centers
2.0
Largest ring
0.0
QED
0.58
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Amino Acids and Derivatives
Endogenous Metabolite
Member status
member
MOA
CRHR1 agonist
Apoptosis Inhibitors
Calcium Channels (Voltage-Gated) alpha2/delta Subunit Ligands
Branched Chain Amino Acid
"CRHR1 agonist
Branched Chain Amino Acid"
Pathway
Metabolic Enzyme/Protease
Source data
