General
Preferred name
EMETINE
Synonyms
Emetine dihydrochloride hydrate ()
ML081 ()
Emetine (dihydrochloride) ()
(+)-Emetine dihydrochloride hydrate ()
EMETINE DIHYDROCHLORIDE ()
Emetine dihydrochloride ()
Emetine dihydrochloride anhydrous ()
(-)-emetine dihydrochloride ()
Hemometina ()
L-emetine dihydrochloride ()
NSC-756754 ()
Emetine Dihydrochloride ()
Emetine hcl ()
EMETINE HYDROCHLORIDE ()
6',7',10,11-TETRAMETHOXYEMETAN ()
EMETAN, 6',7',10,11-TETRAMETHOXY- ()
TCMDC-125531 ()
NSC-33669 ()
CEPHAELINE METHYL ETHER ()
GNF-Pf-196 ()
EMETIN ()
EMETINUM ()
(-)-EMETINE ()
Emetine (hydrochloride hydrate) ()
P&D ID
PD010245
CAS
7083-71-8
316-42-7
83029-37-2
483-18-1
101077-19-4
Tags
available
drug
probe
natural product
drug candidate
Drug indication
Anti-Amebic
Hepatitis virus infection
Drug Status
experimental
approved
investigational
Max Phase
2.0
Probe info
Probe type
experimental probe
Probe sources
Probe targets
[[ compound.targets[t].gene_name ]]
Probe control
Probe control not defined
Orthogonal probes
1
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Emetine is a plant metabolite from ipecac root.
(GtoPdb)
DESCRIPTION
The identification of compounds that selectively inhibit RBBP9 activity may provide valuable probes for the study of apoptosis, cell cycle, and tumorigenesis.
(MLP Probes)
DESCRIPTION
SARS-CoV and SARS-CoV-2 PLpro inhibitor
(Tocris Bioactive Compound Library)
DESCRIPTION
Apoptosis inducer; RNA-Protein translation inhibitor
(LOPAC library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
24
Organisms
9
Compound Sets
22
Cayman Chemical Bioactives
ChEMBL Drugs
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
EU-OPENSCREEN Bioactive Compound Library
EUbOPEN Chemogenomics Library
Guide to Pharmacology
LOPAC library
Mcule NIBR MoA Box Subset
MLP Probes
Novartis Chemogenetic Library (NIBR MoA Box)
NPC Screening Collection
Other bioactive compounds
Reference compounds for characterizing cellular injury in high-content cellular morphology assays
ReFrame library
TargetMol Bioactive Compound Library
Tocris Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
69
Molecular Weight
480.3
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
1
Rotatable Bonds
7
Ring Count
5
Aromatic Ring Count
2
cLogP
4.94
TPSA
52.19
Fraction CSP3
0.59
Chiral centers
4.0
Largest ring
6.0
QED
0.61
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Antitarget
>30 serine proteases
Target
RBBP9
Autophagy
Parasite
RPS2
Pathway
Anti-infection
Microbiology&virology
Primary Target
RNA Polymerase
MOA
Inhibitor
Translation inhibitor
protein synthesis inhibitor
Member status
member
Cellular injury category
Miscellaneous
Recommended Cell Concentration
None
Source data
