General
Preferred name
MOTESANIB DIPHOSPHATE
Synonyms
AMG 706 (Diphosphate) ()
AMG 706 ()
Motesanib (Diphosphate) ()
Motesanib Diphosphate (AMG-706) ()
MOTESANIB PHOSPHATE ()
MOTESANIB ()
P&D ID
PD011164
CAS
857876-30-3
453562-69-1
Tags
available
drug candidate
Drug Status
investigational
Max Phase
3.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
7
AdooQ Bioactive Compound Library
Axon Medchem Screening Library
Cayman Chemical Bioactives
ChEMBL Drugs
EUbOPEN Chemogenomics Library
MedChem Express Bioactive Compound Library
Selleckchem Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
16
Properties
(calculated by RDKit )
Molecular Weight
569.14
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
9
Rotatable Bonds
5
Ring Count
4
Aromatic Ring Count
3
cLogP
2.19
TPSA
234.46
Fraction CSP3
0.23
Chiral centers
0.0
Largest ring
6.0
QED
0.2
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
VEGFR inhibitor
c-Kit
VEGFR
c-Kit,PDGFR,VEGFR
Pathway
Protein Tyrosine Kinase/RTK
Recommended Cell Concentration
None
Source data
