General
Preferred name
ASCOMYCIN
Synonyms
FK520 ()
FR-900520 ()
Immunomycin ()
Ascomycin (FK520) ()
FR 900520, Immunomycin ()
L-683590 ()
P&D ID
PD012698
CAS
104987-12-4
Tags
available
probe
Probe info
Probe selectivity
protein-selective
Probe type
calculated probe
Probe sources
Probe targets
[[ compound.targets[t].gene_name ]]
Probe control
Probe control not defined
Orthogonal probes
2
No orthogonal probes found
Similar probes
1
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
2
Organisms
2
Compound Sets
10
AdooQ Bioactive Compound Library
Cayman Chemical Bioactives
Drug Repurposing Hub
EU-OPENSCREEN Bioactive Compound Library
MedChem Express Bioactive Compound Library
Novartis Chemogenetic Library (NIBR MoA Box)
Probe Miner (suitable probes)
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
24
Properties
(calculated by RDKit )
Molecular Weight
791.48
Hydrogen Bond Acceptors
12
Hydrogen Bond Donors
3
Rotatable Bonds
6
Ring Count
4
Aromatic Ring Count
0
cLogP
4.47
TPSA
178.36
Fraction CSP3
0.81
Chiral centers
14.0
Largest ring
21.0
QED
0.2
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
calcineurin phosphatase
FKBP1A
antibiotic
FKBP
Fungal
Parasite
Member status
member
MOA
calcineurin inhibitor
FKBP12 gene modulator
"Calcineurin inhibitor
FKBP12 gene modulator"
Pathway
Anti-infection
Apoptosis
Autophagy
Cell Cycle/DNA Damage
Immunology/Inflammation
Source data
