General
Preferred name
desoxycortone
Synonyms
deoxycorticosterone ()
DESOXYCORTICOSTERONE ()
11-deoxy Corticosterone ()
P&D ID
PD013278
CAS
64-85-7
Tags
natural product
drug
endogenous
available
Drug indication
Discovery agent
Drug Status
approved
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Administered as desoxycortone pivalate (Zycortal®) as a veterinary medicine to replace the missing in dogs with Addison's disease.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
14
Cayman Chemical Bioactives
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
DrugCentral
DrugCentral Approved Drugs
DrugMAP
EU-OPENSCREEN Bioactive Compound Library
Guide to Pharmacology
MedChem Express Bioactive Compound Library
NPC Screening Collection
NURSA ligand set
Prestwick Chemical Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
54
Properties
(calculated by RDKit )
Molecular Weight
330.22
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
2
Ring Count
4
Aromatic Ring Count
0
cLogP
3.7
TPSA
54.37
Fraction CSP3
0.81
Chiral centers
6.0
Largest ring
6.0
QED
0.84
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
NR3C1, NR3C2
Endogenous Metabolite
Mineralocorticoid Receptor
MOA
mineralocorticoid receptor agonist
Pathway
Metabolic Enzyme/Protease
Vitamin D Related/Nuclear Receptor
Source data