General
Preferred name
CARBOPROST
Synonyms
CARBOPROST TROMETHAMINE ()
15(S)-15-Methyl Prostaglandin F2α ()
15-Methyl-PGF2α ()
Carboprost (tromethamine) ()
15-methyl-pgf2.alpha. ()
(15s)-15-methyl-pgf2.alpha. ()
Hemabate ()
U-32921 ()
15-methylprostaglandin f2.alpha. ()
U-32,921 ()
U-32,921E ()
Carboprost trometamol ()
U-32921E ()
Carboprost tromethamine salt ()
Carboprost Trometanol ()
15(S)-15-methyl Prostaglandin F2.alpha. ()
P&D ID
PD013601
CAS
58551-69-2
59286-19-0
35700-23-3
Tags
available
drug
Approved by
FDA
First approval
1979
Drug indication
Abortion
Oxytocic
Drug Status
approved
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Adrenergic alpha receptor antagonist; antihypertensive (Tocris Bioactive Compound Library)
DESCRIPTION Carboprost is a synthetic prostaglandin analogue of PGF2α with oxytocic properties. It is a potent uterine stimulant and abortifacient which can be given intramuscularly to induce labor. It can also induce luteolysis and reduces serum progesterone concentrations. (BOC Sciences Bioactive Compounds)
Compound Sets
16
BOC Sciences Bioactive Compounds
carboprost-cas-35700-23-3-item-66990
Cayman Chemical Bioactives
16743
ChEMBL Approved Drugs
CHEMBL1237122
CHEMBL1237105
ChEMBL Drugs
CHEMBL1237122
CHEMBL1237105
DrugBank
DB00429
DrugBank Approved Drugs
DB00429
DrugCentral
502
DrugCentral Approved Drugs
502
DrugMAP
DMS3508
DrugMAP Approved Drugs
DMS3508
MedChem Express Bioactive Compound Library
HY-128428
HY-A0195
NCATS Inxight Approved Drugs
7B5032XT6O
NPC Screening Collection
Selleckchem Bioactive Compound Library
carboprost
TargetMol Bioactive Compound Library
T14865
Tocris Bioactive Compound Library
6428
External IDs
48
Properties
(calculated by RDKit )
Molecular Weight
368.26
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
4
Rotatable Bonds
12
Ring Count
1
Aromatic Ring Count
0
cLogP
3.43
TPSA
97.99
Fraction CSP3
0.76
Chiral centers
5.0
Largest ring
5.0
QED
0.31
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Immunology/Inflammation
Target
prostaglandin F2??
Prostaglandin Receptor
Primary Target
Prostanoid Receptors
MOA
Agonist
Therapeutic Class
Abortifacient Agents
Source data