General
Preferred name
DIFLOXACIN
Synonyms
DIFLOXACIN HYDROCHLORIDE ()
Difloxacin HCl ()
Difloxacin (hydrochloride) ()
Difloxacin-d3 ()
Dicural ()
Difloxacin monohydrochloride ()
ABBOTT-56619 ()
NSC-759646 ()
Pulsaflox ()
P&D ID
PD013971
CAS
91296-86-5
98106-17-3
1173147-93-7
Tags
available
drug
drug candidate
Approved by
FDA
Drug Status
vet_approved
approved
Drug indication
Anti-Infective (DNA gyrase inhibitor)
First approval
1998
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Difloxacin is a second-generation, synthetic fluoroquinolone antibacterial. It has broad-spectrum activity against Gram +ve and Gram -ve bacteria.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
13
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
Guide to Pharmacology
MedChem Express Bioactive Compound Library
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
41
Molecular Weight
399.14
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
1
Rotatable Bonds
3
Ring Count
4
Aromatic Ring Count
3
cLogP
2.72
TPSA
65.78
Fraction CSP3
0.24
Chiral centers
0.0
Largest ring
6.0
QED
0.73
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Microbiology&virology
Anti-infection
Target
Bacterial
antibiotic
Antibiotics
Indication
skin infections, urinary tract infections
MOA
bacterial DNA gyrase inhibitor
Source data
