General
Preferred name
FLUINDIONE
Synonyms
Fluindionum ()
2-(p-fluorophenyl)-1,3-indandione ()
Fluindiona ()
Previsccan ()
Previscan ()
P&D ID
PD014103
CAS
957-56-2
Tags
available
drug
Drug Status
approved
investigational
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Fluindione is a vitamin K antagonist with anticoagulant applications. It is under investigation for the treatment of venous thrombosis, pulmonary embolism, permanent atrial fibrillation, and blood coagulation disorders.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
11
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMatrix
NPC Screening Collection
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
25
Molecular Weight
240.06
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
0
Rotatable Bonds
1
Ring Count
3
Aromatic Ring Count
2
cLogP
2.99
TPSA
34.14
Fraction CSP3
0.07
Chiral centers
0.0
Largest ring
6.0
QED
0.72
Structural alerts
1
keto_keto_beta_A(68)
c:1-2:c(:c:c:c:c:1)-[#6](=[#8])-[#6;X4]-[#6]-2=[#8]
PAINS Family B
Related compounds
Custom attributes
(extracted from source data)
Source data
