General
Preferred name
HYPOTAURINE
Synonyms
2-Aminoethanesulfinic acid ()
2-Aminoethylsulfinic acid ()
P&D ID
PD015114
CAS
300-84-5
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Antioxidant that binds hydroxyl radicals; GABA transport inhibitor (LOPAC library)
DESCRIPTION Non-selective, endogenous glycine receptor partial agonist (Tocris Bioactive Compound Library)
DESCRIPTION Hypotaurine is an endogenous inhibitory amino acid for glycine receptor (GlyR). It acts as an antioxidant and a protective agent under physiological conditions. (BOC Sciences Bioactive Compounds)
Compound Sets
6
BOC Sciences Bioactive Compounds
hypotaurine-cas-300-84-5-105266
Cayman Chemical Bioactives
29614
LOPAC library
MedChem Express Bioactive Compound Library
HY-100803
TargetMol Bioactive Compound Library
T5225
Tocris Bioactive Compound Library
0208
External IDs
32
Properties
(calculated by RDKit )
Molecular Weight
109.02
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
2
Ring Count
0
Aromatic Ring Count
0
cLogP
-0.83
TPSA
63.32
Fraction CSP3
1.0
Chiral centers
1.0
Largest ring
0.0
QED
0.45
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Selectivity
Antioxidant
Pathway
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Target
Glycine receptor
Endogenous Metabolite
Primary Target
Glycine Receptors
MOA
Agonist
Chloride Channel
Source data