General
Preferred name
ML060
Synonyms
P&D ID
PD016063
Tags
probe
nuisance
Probe info
Probe type
experimental probe
Probe sources
MLP Probes
Probe targets
[[ compound.targets[t].gene_name ]]
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Heat shock protein 90 (Hsp90) is the essential molecular chaperone which regulates a variety of cellular functions including development, cell cycle, and steroid hormone signaling. The disruption of interaction between the C-terminal portion of Hsp90 and TPR2A domain of HOP may regulate the Hsp90 functions.
(MLP Probes)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
2
Organisms
0
Compound Sets
3
LSP-MoA library (Laboratory of Systems Pharmacology)
MLP Probes
Nuisance compounds in cellular assays
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
12
Molecular Weight
235.11
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
0
Rotatable Bonds
2
Ring Count
2
Aromatic Ring Count
0
cLogP
-0.67
TPSA
82.67
Fraction CSP3
0.5
Chiral centers
0.0
Largest ring
6.0
QED
0.69
Structural alerts
1
Redox
Redox cycling
Nuisance compounds in cellular assays
Related compounds
Custom attributes
(extracted from source data)
Source data
