General
Preferred name
LICARBAZEPINE
Synonyms
BIA 2-005 ()
GP 47779 ()
?10,11-hydroxy-10,11 Dihydrocarbamezer ()
?10,11-dihydro-10-hydroxy Carbamazepine ()
10-hydroxy-carbamazepine ()
P&D ID
PD017222
CAS
29331-92-8
Tags
available
drug candidate
Drug indication
Bipolar disorder
Drug Status
investigational
Max Phase
3.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Active metabolite of oxcarbazepine (Cat. No. 3864)
(Tocriscreen Plus)
DESCRIPTION
TRPV1 antagonist
(Tocris Bioactive Compound Library)
DESCRIPTION
Active metabolite of oxcarbazepine (Cat. No. 3684)
(Tocriscreen Total)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
10
Cayman Chemical Bioactives
ChEMBL Drugs
DrugMAP
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
ReFrame library
TargetMol Bioactive Compound Library
Tocris Bioactive Compound Library
Tocriscreen Plus
Tocriscreen Total
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
24
Molecular Weight
254.11
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
0
Ring Count
3
Aromatic Ring Count
2
cLogP
2.49
TPSA
66.56
Fraction CSP3
0.13
Chiral centers
1.0
Largest ring
7.0
QED
0.76
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target Type
Ion Channels
Primary Target
Voltage-gated Sodium (NaV) Channels
MOA
Blocker
Pathway
Membrane Transporter/Ion Channel
Target
Sodium Channel
Source data
