General
Preferred name
NARINGIN
Synonyms
Naringoside ()
Naringin hydrate ()
Naringin (Naringoside) ()
P&D ID
PD017564
CAS
10236-47-2
11032-30-7
Tags
natural product
drug candidate
available
Drug indication
Discovery agent
Drug Status
investigational
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Naringin is the foremost flavonoid in grapefruit and is reported to have a deleterious effect on intestinal drug absorption by inhibiting the transport protein OATP1A2 .
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
14
AdooQ Bioactive Compound Library
Cayman Chemical Bioactives
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
Drug Repurposing Hub
DrugBank
DrugMAP
Guide to Pharmacology
MedChem Express Bioactive Compound Library
Other bioactive compounds
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
45
Molecular Weight
580.18
Hydrogen Bond Acceptors
14
Hydrogen Bond Donors
8
Rotatable Bonds
6
Ring Count
5
Aromatic Ring Count
2
cLogP
-1.17
TPSA
225.06
Fraction CSP3
0.52
Chiral centers
11.0
Largest ring
6.0
QED
0.2
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Metabolism
Autophagy
Metabolic Enzyme/Protease
Target
CYP450
SLCO1A2
Cytochrome P450
Endogenous Metabolite
Mitophagy
P450 (e.g. CYP17)
MOA
Cytochrome P450 inhibitor
Source data
