General
Preferred name
PP 3
Synonyms
4-AMino-1-phenylpyrazolo[3,4-d]pyriMidine ()
PP3 ()
P&D ID
PD018549
CAS
5334-30-5
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION PP3 is an inactive analogue of the Src tyrosine kinase inhibitor . (GtoPdb)
DESCRIPTION Cyclooxygenase inhibitor (COX-1 > COX-2) (Tocris Bioactive Compound Library)
DESCRIPTION PP 3 is an inactive analog of the Src tyrosine kinase inhibitors PP1 and PP2. It inhibits EGFR kinase (IC50 = 2.7 μM). (BOC Sciences Bioactive Compounds)
Compound Sets
7
BOC Sciences Bioactive Compounds
pp-3-cas-5334-30-5-item-25805
Cayman Chemical Bioactives
15595
Guide to Pharmacology
6029
MedChem Express Bioactive Compound Library
HY-108484
Selleckchem Bioactive Compound Library
4-amino-1-phenylpyrazolo-3-4-d-pyrimidine
TargetMol Bioactive Compound Library
T23176
Tocris Bioactive Compound Library
2794
External IDs
19
Properties
(calculated by RDKit )
Molecular Weight
211.09
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
1
Rotatable Bonds
1
Ring Count
3
Aromatic Ring Count
3
cLogP
1.4
TPSA
69.62
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.66
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Pathway
Angiogenesis
Tyrosine Kinase/Adaptors
JAK/STAT Signaling
Protein Tyrosine Kinase/RTK
Target
Src kinase
EGFR
Primary Target
Src Kinases
MOA
Inhibitor
Source data