General
Preferred name
KL001
Synonyms
KL 001 ()
KL-001 ()
P&D ID
PD019501
CAS
309928-48-1
Tags
available
drug candidate
Drug indication
Glioblastoma of brain
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Cryptochrome protein stabilizer; lengthens circadian period
(Tocriscreen Plus)
DESCRIPTION
Core binding factor inhibitor; attenuates hematopoiesis
(Tocris Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
11
Axon Medchem Screening Library
Cayman Chemical Bioactives
DrugMAP
Enamine BioReference Compounds
Mcule NIBR MoA Box Subset
MedChem Express Bioactive Compound Library
Novartis Chemogenetic Library (NIBR MoA Box)
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
Tocris Bioactive Compound Library
Tocriscreen Plus
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
10
Molecular Weight
398.13
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
1
Rotatable Bonds
7
Ring Count
4
Aromatic Ring Count
4
cLogP
3.21
TPSA
75.68
Fraction CSP3
0.24
Chiral centers
1.0
Largest ring
6.0
QED
0.52
QED
0.52
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target Type
Cell Biology
Target
Cryptochrome protein (CRY)
Cryptochrome stabilizer
Cryptochrome
Primary Target
Other Transcription Factors
Member status
member
MOA
CRY1, CRY2 stabilizer
Pathway
Metabolic Enzyme/Protease
Source data
