General
Preferred name
oxytocin
Synonyms
Oxytocic hormone acetate ()
??-Hypophamine acetate ()
Oxytocic hormone ()
??-Hypophamine ()
Oxytocin acetate ()
Oxytocin (Syntocinon) ()
¦Á-Hypophamine ()
α-Hypophamine ()
oxytocin, inhaled, GlaxoSmithKline ()
H-Cys(1)-Tyr-Ile-Gln-Asn-Cys(1)-Pro-Leu-Gly-NH2 ()
[3H]OT (human, mouse, rat) ()
TNX1900 ()
Oxitocina ()
Oxytocine ()
Oxytocinum ()
Syntocinon ()
Endopituitrina ()
Alpha-hypophamine ()
Pitocin ()
Intertocine s ()
Orasthin ()
TTA-121 ()
TNX-1900 ()
Syntometrine ()
Oxytocin (acetate) ()
P&D ID
PD019681
CAS
6233-83-6
50-56-6
Tags
available
drug
Approved by
FDA
First approval
1980
Drug indication
Lactation failure
Autism spectrum disorder
Oxytocic
Drug Status
approved
vet_approved
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Inhibitor of alpha-MSH release; inhibits opioid effects in vivo (Tocris Bioactive Compound Library)
Cell lines
0
Organisms
1
Compound Sets
18
Cayman Chemical Bioactives
11799
ChEMBL Approved Drugs
CHEMBL395429
ChEMBL Drugs
CHEMBL395429
Drug Repurposing Hub
DrugCentral
2042
DrugCentral Approved Drugs
2042
DrugMAP
DMDL27I
DrugMAP Approved Drugs
DMDL27I
Guide to Pharmacology
2174
2176
JUMP-Target 1 Compound Set
439302
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL395429
Mcule NIBR MoA Box Subset
MCULE-1193319923
MedChem Express Bioactive Compound Library
HY-17571
Novartis Chemogenetic Library (NIBR MoA Box)
ReFrame library
Selleckchem Bioactive Compound Library
Oxytocin-Acetate(Syntocinon)
TargetMol Bioactive Compound Library
T5026
T5145
Tocris Bioactive Compound Library
1910
External IDs
49
Properties
(calculated by RDKit )
Molecular Weight
1006.44
Hydrogen Bond Acceptors
15
Hydrogen Bond Donors
12
Rotatable Bonds
17
Ring Count
3
Aromatic Ring Count
1
cLogP
-3.61
TPSA
399.53
Fraction CSP3
0.6
Chiral centers
9.0
Largest ring
20.0
QED
0.07
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Endocrinology/Hormones
GPCR/G protein
Metabolic Enzyme/Protease
Target
Oxytocin Receptor
AVPR1A, AVPR1B, AVPR2, OXTR
AVPR1A
Endogenous Metabolite
Primary Target
Oxytocin Receptors
MOA
Agonist
OXTR agonist
oxytocin receptor agonist
Member status
member
Indication
labor induction
Source data