General
Preferred name
SPHINGOSINE
Synonyms
D-erythro-Sphingosine (synthetic) ()
Erythrosphingosine (hydrochloride) ()
erythro-C18-Sphingosine (hydrochloride) ()
trans-4-Sphingenine (hydrochloride) ()
D-ERYTHRO-SPHINGOSINE ()
D-erythro-Sphingosine (hydrochloride) ()
2-amino-4-trans-octadecene-1,3-diol,C18 Sphingosine ()
D-Sphingosine ()
?Sphingosine (d18:1) ()
Sphingosine-d9 (d18:1) ()
Sphingosine-d7 (d18:1) ()
Sphingosine-13C2-d2 (d18:1) ()
Erythrosphingosine ()
erythro-C18-Sphingosine ()
trans-4-Sphingenine ()
P&D ID
PD019972
CAS
123-78-4
475662-41-0
477243-03-1
10140-30-4
2673-72-5
2377379-55-8
1246304-34-6
2692623-81-5
Tags
available
drug candidate
Drug Status
experimental
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION 5-, 12-, 15-Lipoxygenase inhibitor (Tocris Bioactive Compound Library)
Cell lines
2
Organisms
3
Compound Sets
14
Cayman Chemical Bioactives
10007907
24371
22786
27875
Concise Guide to Pharmacology 2017/18
2452
Concise Guide to Pharmacology 2019/20
2452
Concise Guide to Pharmacology 2021/22
2452
Concise Guide to Pharmacology 2023/24
2452
DrugBank
DB03203
DrugMAP
DMO1FTI
EU-OPENSCREEN Bioactive Compound Library
EOS101377
Guide to Pharmacology
2452
Mcule NIBR MoA Box Subset
MCULE-7184041607
MedChem Express Bioactive Compound Library
HY-101047
HY-W089922
Novartis Chemogenetic Library (NIBR MoA Box)
Selleckchem Bioactive Compound Library
sphingosine
Tocris Bioactive Compound Library
0633
External IDs
63
Properties
(calculated by RDKit )
Molecular Weight
299.28
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
3
Rotatable Bonds
15
Ring Count
0
Aromatic Ring Count
0
cLogP
3.92
TPSA
66.48
Fraction CSP3
0.89
Chiral centers
2.0
Largest ring
0.0
QED
0.32
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Primary Target
Protein Kinase C
MOA
Inhibitor
Ceramidase Inhibitors
Member status
virtual
Pathway
Epigenetics
Metabolic Enzyme/Protease
TGF-beta/Smad
Membrane Transporter/Ion Channel
Neuronal Signaling
Target
Endogenous Metabolite
phosphatase
PKC
TRP Channel
Source data