General
Preferred name
LEUKOTRIENE D4
Synonyms
LTD4 ()
Leukotriene d ()
Leukotriene D4-d5 ()
P&D ID
PD021018
CAS
73836-78-9
1240398-17-7
Tags
available
drug candidate
Drug indication
Discovery agent
Drug Status
investigational
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Leukotriene D4 is a constituent of slow-reacting substance of anaphylaxis (SRS-A) and acts as an agonist of smooth muscle contraction. LTD4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute hypersensitivity. (BOC Sciences Bioactive Compounds)
Cell lines
0
Organisms
1
Compound Sets
6
BOC Sciences Bioactive Compounds
leukotriene-d4-cas-73836-78-9-item-190944
Cayman Chemical Bioactives
10006199
20310
ChEMBL Drugs
CHEMBL288943
DrugBank
DB11858
DrugMAP
DMIUZX3
Novartis Chemogenetic Library (NIBR MoA Box)
External IDs
31
Properties
(calculated by RDKit )
Molecular Weight
496.26
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
5
Rotatable Bonds
20
Ring Count
0
Aromatic Ring Count
0
cLogP
3.43
TPSA
149.95
Fraction CSP3
0.56
Chiral centers
3.0
Largest ring
0.0
QED
0.1
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Member status
virtual
MOA
CYSLTR1 agonist
CYSLTR2 agonist
Source data