General
Preferred name
ARP 100
Synonyms
ARP100 ()
ARP-100 ()
MMP-2 Inhibitor III, Compound 10a ()
P&D ID
PD021431
CAS
704888-90-4
Tags
available
drug candidate
Drug indication
Discovery agent
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Inhibitor of MMP-2 (Tocris Bioactive Compound Library)
DESCRIPTION ARP 100 has been found to be a selective inhibitor of MMP-2 and could show anti-invasive properties in HT1080 fibrosarcoma cells at some extent. (BOC Sciences Bioactive Compounds)
Compound Sets
11
BOC Sciences Bioactive Compounds
arp-100-cas-704888-90-4-item-129473
Cayman Chemical Bioactives
13321
Concise Guide to Pharmacology 2017/18
5140
Concise Guide to Pharmacology 2019/20
5140
Concise Guide to Pharmacology 2021/22
5140
Concise Guide to Pharmacology 2023/24
5140
DrugMAP
DM6KQXF
Guide to Pharmacology
5140
MedChem Express Bioactive Compound Library
HY-103444
Selleckchem Bioactive Compound Library
arp-100
Tocris Bioactive Compound Library
2621
External IDs
20
Properties
(calculated by RDKit )
Molecular Weight
364.11
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
2
Rotatable Bonds
7
Ring Count
2
Aromatic Ring Count
2
cLogP
2.19
TPSA
95.94
Fraction CSP3
0.24
Chiral centers
0.0
Largest ring
6.0
QED
0.58
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Primary Target
Matrix Metalloproteases
MOA
Inhibitor
Pathway
Metabolic Enzyme/Protease
Target
MMP
Source data