General
Preferred name
Uridine-5'-Diphosphate
Synonyms
Uridine 5'-diphosphate sodium ()
URIDINE_DIPHOSPHATE ()
Uridine 5'-diphosphate disodium salt hyd ()
UDP disodium salt ()
Uridine-5'-diphosphate disodium salt ()
UDP ()
uridine diphosphate ()
Uridine 5'-Diphosphate ()
UDP (sodium salt hydrate) ()
P&D ID
PD048470
CAS
27821-45-0
58-98-0
Tags
available
drug candidate
Drug indication
Discovery agent
Drug Status
experimental
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION High affinity, potent CCR2 antagonist (Tocris Bioactive Compound Library)
DESCRIPTION P2Y receptor agonist (LOPAC library)
Compound Sets
18
Cayman Chemical Bioactives
18137
Concise Guide to Pharmacology 2017/18
1749
Concise Guide to Pharmacology 2019/20
1749
Concise Guide to Pharmacology 2021/22
1749
Concise Guide to Pharmacology 2023/24
1749
DrugBank
DB03435
DrugMAP
DMDQKJB
EUbOPEN Chemogenomics Library
EUB0000457
Guide to Pharmacology
1749
LOPAC library
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL130266
Mcule NIBR MoA Box Subset
MCULE-3413031259
MedChem Express Bioactive Compound Library
HY-W010832
Novartis Chemogenetic Library (NIBR MoA Box)
Selleckchem Bioactive Compound Library
uridine-5-diphosphate-disodium-salt
TargetMol Bioactive Compound Library
T4706
Tocris Bioactive Compound Library
3111
ZINC Tool Compounds
ZINC000004490939
External IDs
61
Properties
(calculated by RDKit )
Molecular Weight
404.0
Hydrogen Bond Acceptors
10
Hydrogen Bond Donors
6
Rotatable Bonds
6
Ring Count
2
Aromatic Ring Count
1
cLogP
-2.62
TPSA
217.84
Fraction CSP3
0.56
Chiral centers
5.0
Largest ring
6.0
QED
0.27
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
P2Y
Pathway
Neuroscience
Cell Cycle/DNA Damage
GPCR/G protein
Metabolic Enzyme/Protease
Target
P2Y6
P2Y14
DNA/RNA Synthesis
Endogenous Metabolite
P2Y Receptor
P2 Receptor
Primary Target
Purinergic (P2Y) Receptors
Member status
virtual
MOA
P2Y6 purinoceptor antagonist
Recommended Cell Concentration
None
Source data