General
Preferred name
PMID18068976C25
Synonyms
compound 25 [PMID: 18068976] ()
P&D ID
PD050015
Tags
drug candidate
Drug indication
Discovery agent
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Compound 25 is reported to selectively inhibit the activity of ADAM metallopeptidase domain 10 (ADAM10), relative to MMP1 and MMP2 .
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
8
Molecular Weight
523.24
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
3
Rotatable Bonds
6
Ring Count
4
Aromatic Ring Count
1
cLogP
2.14
TPSA
136.48
Fraction CSP3
0.68
Chiral centers
2.0
Largest ring
6.0
QED
0.38
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Source data
