General
Preferred name
PMID11934595C2
Synonyms
compound 2 [PMID: 11934595] ()
P&D ID
PD050019
Tags
drug candidate
Drug indication
Discovery agent
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Compound 2 is reported as an inhibitor of bone morphogenetic protein 1 (BMP1), or procollagen C-proteinase in this referenced article . BMP1 is considered a druggable molecular target for the development of anti-fibrotic agents because collagen substrates are involved in forming functional collagen fibrils. (GtoPdb)
Compound Sets
2
DrugMAP
DMU0AGE
Guide to Pharmacology
8562
External IDs
8
Properties
(calculated by RDKit )
Molecular Weight
490.09
Hydrogen Bond Acceptors
8
Hydrogen Bond Donors
2
Rotatable Bonds
9
Ring Count
4
Aromatic Ring Count
3
cLogP
2.79
TPSA
114.4
Fraction CSP3
0.23
Chiral centers
1.0
Largest ring
6.0
QED
0.35
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Source data