General
Preferred name
ROBALZOTAN
Synonyms
NAD 299 hydrochloride ()
[3H]robalzotan ()
[3H]robalzotan ()
Robalzotan tartrate hydrate ()
NAD-299 ()
AZD-7371 ()
P&D ID
PD050602
CAS
184674-99-5
169758-66-1
Tags
available
drug candidate
Drug indication
Anxiety disorder
Discovery agent
Drug Status
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Selective alpha1B antagonist
(Tocris Bioactive Compound Library)
DESCRIPTION
Selective, high affinity 5-HT1A antagonist
(Tocriscreen Plus)
DESCRIPTION
NAD 299 hydrochloride is a 5-HT1A receptor antagonist. It can be used in psychotropic drug development.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
14
BOC Sciences Bioactive Compounds
ChEMBL Drugs
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
DrugBank
ReFrame library
Tocris Bioactive Compound Library
Tocriscreen Plus
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
30
Molecular Weight
318.17
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
4
Ring Count
4
Aromatic Ring Count
1
cLogP
2.64
TPSA
55.56
Fraction CSP3
0.61
Chiral centers
1.0
Largest ring
6.0
QED
0.93
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target Type
7-TM Receptors
Primary Target
5-HT1A Receptors
MOA
Antagonist
serotonin receptor antagonist
Target
HTR1A
Source data
